Ya, but they probably collapsed on their own. Lacked the technologies needed for sustained urbanization. (And if you read about Cahokia a little, you find that "urban" in the European sense isn't terribly applicable. There are pretty serious keystone technologies that allow people to live at such densities without snuffing themselves out that they simply didn't have access to. We went over this last time you brought it up.) No reason to think it was European disease that did for them. The population levels the Europeans found, in addition to the centuries it took for the Mesoamericans to develop such complex societies...no way the population was wiped out that early. The Spanish would have been pretty bored to find everything cut off at the knees centuries earlier.
The theorizing above is interesting, but its theorizing regardless. Occam's Razor and all that jazz. Presenting it as some sort of accepted truth is pretty far out. Its just a neat set of ideas.