Economy. Both support mixed economy controlled by a central bank check
Taxes. Both support the IRS in it's current form and neither has any real plans to reform it. check
National defense spending. Same old spending, same old wars check
Foreign policy. Bully and invade foreign nations in order to control the markets for their resources check
Social programs (independent of issues, such as abortion, programs are institutionalized, have staffs, have budgets, and have oversight). This is the only difference.
Domestic policy (education, energy, etc.). Pretty much exactly the same. Both are for centrally controlled state education, similar energy policies, similar environmental program (do nothing), both are corporate shills and do whatever corporations want in their day to day dealings. Check.
Both are nearly identical at every turn. At best they have some slight differences but what it amounts to is merely slightly differently administered versions of the same corporate/consumerist system of control, neither version is true democracy.
Both are the same form of absolute rule by a technocratic elite with only a semblance of democracy. There would be no significant or profound change if either party won over the other. I hesitate to even call what they do leadership because I think most of what's going on in human society is simply instinctive mass behavior, like the dancing of bees, that they have designed systems to take of advantage of.